BRCA1 regulates the cancer stem cell fate of breast cancer cells in the context of hypoxia and histone deacetylase inhibitors

Cancer cell stemness is essential for enabling malignant progression and clonal evolution. Cancer cell fate is likely determined by complex mechanisms involving both cell-intrinsic pathways and stress signals from tumor microenvironment. In this study, we examined the role of the tumor suppressor BR...

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Detalles Bibliográficos
Autores principales: Kim, Hoon, Lin, Qun, Yun, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609720/
https://www.ncbi.nlm.nih.gov/pubmed/31273285
http://dx.doi.org/10.1038/s41598-019-46210-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609720/
https://www.ncbi.nlm.nih.gov/pubmed/31273285
http://dx.doi.org/10.1038/s41598-019-46210-y

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