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The β‐domain of streptokinase affects several functionalities, including specific/proteolytic activity kinetics

Streptokinase (SK) is a plasminogen activator which converts inactive plasminogen (Pg) to active plasmin (Pm), which cleaves fibrin clots. SK secreted by groups A, C, and G Streptococcus (SKA/SKC/SKG) is composed of three domains: SKα, SKβ and SKγ. Previous domain‐swapping studies between SK1/SK2b‐c...

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Detalles Bibliográficos
Autores principales: Rafipour, Maryam, Keramati, Malihe, Aslani, Mohammad Mehdi, Arashkia, Arash, Roohvand, Farzin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609762/
https://www.ncbi.nlm.nih.gov/pubmed/31087538
http://dx.doi.org/10.1002/2211-5463.12657