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Eribulin penetrates brain tumor tissue and prolongs survival of mice harboring intracerebral glioblastoma xenografts

Glioblastoma is one of the most devastating human malignancies for which a novel efficient treatment is urgently required. This pre–clinical study shows that eribulin, a specific inhibitor of telomerase reverse transcriptase (TERT)‐RNA‐dependent RNA polymerase, is an effective anticancer agent again...

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Detalles Bibliográficos
Autores principales: Takahashi, Masamichi, Miki, Shunichiro, Fujimoto, Kenji, Fukuoka, Kohei, Matsushita, Yuko, Maida, Yoshiko, Yasukawa, Mami, Hayashi, Mitsuhiro, Shinkyo, Raku, Kikuchi, Kiyomi, Mukasa, Akitake, Nishikawa, Ryo, Tamura, Kenji, Narita, Yoshitaka, Hamada, Akinobu, Masutomi, Kenkichi, Ichimura, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609810/
https://www.ncbi.nlm.nih.gov/pubmed/31099446
http://dx.doi.org/10.1111/cas.14067