miR-103/107 prolong Wnt/β-catenin signaling and colorectal cancer stemness by targeting Axin2

Cancer stemness drives tumor initiation, progression, metastasis, recurrence, and therapy resistance. However, mechanisms that potentiate the acquisition and maintenance of stemness fate of cancer cells remain incompletely understood. Here, we show that miR-103/107 stimulate multiple stem-like featu...

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Detalles Bibliográficos
Autores principales: Chen, Hsin-Yi, Lang, Yaw-Dong, Lin, Han-Nan, Liu, Yun-Ru, Liao, Chun-Chieh, Nana, André Wendindondé, Yen, Yun, Chen, Ruey-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609830/
https://www.ncbi.nlm.nih.gov/pubmed/31273221
http://dx.doi.org/10.1038/s41598-019-41053-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609830/
https://www.ncbi.nlm.nih.gov/pubmed/31273221
http://dx.doi.org/10.1038/s41598-019-41053-z

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