Cargando…
miR-103/107 prolong Wnt/β-catenin signaling and colorectal cancer stemness by targeting Axin2
Cancer stemness drives tumor initiation, progression, metastasis, recurrence, and therapy resistance. However, mechanisms that potentiate the acquisition and maintenance of stemness fate of cancer cells remain incompletely understood. Here, we show that miR-103/107 stimulate multiple stem-like featu...
Autores principales: | Chen, Hsin-Yi, Lang, Yaw-Dong, Lin, Han-Nan, Liu, Yun-Ru, Liao, Chun-Chieh, Nana, André Wendindondé, Yen, Yun, Chen, Ruey-Hwa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609830/ https://www.ncbi.nlm.nih.gov/pubmed/31273221 http://dx.doi.org/10.1038/s41598-019-41053-z |
Ejemplares similares
-
Limited dishevelled/Axin oligomerization determines efficiency of Wnt/β-catenin signal transduction
por: Kan, Wei, et al.
Publicado: (2020) -
Bili Inhibits Wnt/β-Catenin Signaling by Regulating the Recruitment of Axin to LRP6
por: Kategaya, Lorna S., et al.
Publicado: (2009) -
USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin
por: Ji, Lei, et al.
Publicado: (2019) -
The SIAH E3 ubiquitin ligases promote Wnt/β-catenin signaling through mediating Wnt-induced Axin degradation
por: Ji, Lei, et al.
Publicado: (2017) -
SIRT4-Catalyzed Deacetylation of Axin1 Modulates the Wnt/β-Catenin Signaling Pathway
por: Wang, Yuting, et al.
Publicado: (2022)