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Extrachromosomal circular DNAs: an extra piece of evidence to depict tumor heterogeneity
The tumor microenvironment (TME) comprises a heterogeneous number and type of cellular and noncellular components that vary in the context of molecular, genomic and epigenomic levels. The genotypic diversity and plasticity within cancer cells are known to be affected by genomic instability and genom...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Science Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609892/ https://www.ncbi.nlm.nih.gov/pubmed/31285839 http://dx.doi.org/10.2144/fsoa-2019-0024 |