Mendelian Randomization Analysis of Hemoglobin A(1c) as a Risk Factor for Coronary Artery Disease

OBJECTIVE: Observational studies show that higher hemoglobin A(1c) (A1C) predicts coronary artery disease (CAD). It remains unclear whether this association is driven entirely by glycemia. We used Mendelian randomization (MR) to test whether A1C is causally associated with CAD through glycemic and/o...

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Detalles Bibliográficos
Autores principales: Leong, Aaron, Chen, Ji, Wheeler, Eleanor, Hivert, Marie-France, Liu, Ching-Ti, Merino, Jordi, Dupuis, Josée, Tai, E Shyong, Rotter, Jerome I., Florez, Jose C., Barroso, Inês, Meigs, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2019
Materias:
Epidemiology/Health Services Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609962/
https://www.ncbi.nlm.nih.gov/pubmed/30659074
http://dx.doi.org/10.2337/dc18-1712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609962/
https://www.ncbi.nlm.nih.gov/pubmed/30659074
http://dx.doi.org/10.2337/dc18-1712

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