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Bile cell-free DNA as a novel and powerful liquid biopsy for detecting somatic variants in biliary tract cancer

Tissue sampling of biliary tract carcinomas (BTCs) for molecular characterization is challenging. The aim of this study was to investigate the possibility of identifying individual actionable mutations derived from bile cell-free DNA (cfDNA) using targeted deep sequencing. Ten BTC patients, four wit...

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Detalles Bibliográficos
Autores principales: Shen, Ningjia, Zhang, Dadong, Yin, Lei, Qiu, Yinghe, Liu, Jian, Yu, Wenlong, Fu, Xiaohui, Zhu, Bin, Xu, Xiaoya, Duan, Anqi, Chen, Zishuo, Wang, Xiang, Cao, Xinkai, Zhao, Teng, Zhou, Zisong, Yu, Lianghe, Qin, Hao, Fang, Zheng, Li, Jing-Yu, Liu, Yuanjin, Xiong, Lei, Yuan, Bo, Li, Fugen, Zhang, Yongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610033/
https://www.ncbi.nlm.nih.gov/pubmed/31173267
http://dx.doi.org/10.3892/or.2019.7177