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Estimation of Transcription Factor Activity in Knockdown Studies
Numerous methods have been developed trying to infer actual regulatory events in a sample. A prominent class of methods model genome-wide gene expression as linear equations derived from a transcription factor (TF) – gene network and optimizes parameters to fit the measured expression intensities. W...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610105/ https://www.ncbi.nlm.nih.gov/pubmed/31270369 http://dx.doi.org/10.1038/s41598-019-46053-7 |