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Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis

β-Arrestins are major regulators of G protein-coupled receptor-mediated signaling processes. Their potential roles in regulating adipocyte function in vivo remain unexplored. Here we report the novel finding that mice lacking β-arrestin-2 (barr2) selectively in adipocytes show significantly reduced...

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Detalles Bibliográficos
Autores principales: Pydi, Sai P., Jain, Shanu, Tung, Wesley, Cui, Yinghong, Zhu, Lu, Sakamoto, Wataru, Jain, Shalini, Abel, Brent S., Skarulis, Monica C., Liu, Jie, Huynh, Thanh, Pacak, Karel, Caron, Marc G., Gavrilova, Oksana, Finkel, Toren, Wess, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610117/
https://www.ncbi.nlm.nih.gov/pubmed/31270323
http://dx.doi.org/10.1038/s41467-019-11003-4