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Neuroepigenetic signatures of age and sex in the living human brain

Age- and sex-related alterations in gene transcription have been demonstrated, however the underlying mechanisms are unresolved. Neuroepigenetic pathways regulate gene transcription in the brain. Here, we measure in vivo expression of the epigenetic enzymes, histone deacetylases (HDACs), across heal...

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Detalles Bibliográficos
Autores principales: Gilbert, Tonya M., Zürcher, Nicole R., Catanese, Mary C., Tseng, Chieh-En J., Di Biase, Maria A., Lyall, Amanda E., Hightower, Baileigh G., Parmar, Anjali J., Bhanot, Anisha, Wu, Christine J., Hibert, Matthew L., Kim, Minhae, Mahmood, Umar, Stufflebeam, Steven M., Schroeder, Frederick A., Wang, Changning, Roffman, Joshua L., Holt, Daphne J., Greve, Douglas N., Pasternak, Ofer, Kubicki, Marek, Wey, Hsiao-Ying, Hooker, Jacob M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610136/
https://www.ncbi.nlm.nih.gov/pubmed/31270332
http://dx.doi.org/10.1038/s41467-019-11031-0