Inflammasome-Driven Interleukin-1α and Interleukin-1β Production in Atherosclerotic Plaques Relates to Hyperlipidemia and Plaque Complexity

CANTOS (Canakinumab Antiinflammatory Thrombosis Outcome Study) confirmed interleukin (IL)–1β as an appealing therapeutic target for human atherosclerosis and related complications. However, there are serious gaps in our understanding of IL-1 production in atherosclerosis. Herein the authors show tha...

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Detalles Bibliográficos
Autores principales: Jiang, Xintong, Wang, Feilong, Wang, Yajuan, Gisterå, Anton, Roy, Joy, Paulsson-Berne, Gabrielle, Hedin, Ulf, Lerman, Amir, Hansson, Göran K., Herrmann, Joerg, Yan, Zhong-qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
CLINICAL RESEARCH
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610158/
https://www.ncbi.nlm.nih.gov/pubmed/31312755
http://dx.doi.org/10.1016/j.jacbts.2019.02.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610158/
https://www.ncbi.nlm.nih.gov/pubmed/31312755
http://dx.doi.org/10.1016/j.jacbts.2019.02.007

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