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A New Method for Ethical and Efficient Evidence Generation for Off-Label Medication Use in Oncology (A Case Study in Glioblastoma)

In oncology, preclinical and early clinical data increasingly support the use of a number of candidate “non-cancer” drugs in an off-label setting against multiple tumor types. In particular, metabolically targeted drugs show promise as adjuvant chemo and radiosensitizers, improving or restoring sens...

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Detalles Bibliográficos
Autores principales: Agrawal, Samir, Vamadevan, Padman, Mazibuko, Ndaba, Bannister, Robin, Swery, Raphael, Wilson, Shanna, Edwards, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610246/
https://www.ncbi.nlm.nih.gov/pubmed/31316378
http://dx.doi.org/10.3389/fphar.2019.00681