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Sp1 contributes to radioresistance of cervical cancer through targeting G2/M cell cycle checkpoint CDK1

BACKGROUND/AIMS: Radioresistance remains a significant obstacle in the therapy of cervical cancer, and the mechanism of it is still unclear. We aimed to investigate the role of specificity protein 1 (Sp1) in radioresistance of cervical cancer. METHODS: Sp1 was examined immunohistochemically on tissu...

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Detalles Bibliográficos
Autores principales: Deng, Yuan-Run, Chen, Xiao-Jing, Chen, Wei, Wu, Lan-Fang, Jiang, Hui-Ping, Lin, Dan, Wang, Li-Jing, Wang, Wei, Guo, Sui-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610296/
https://www.ncbi.nlm.nih.gov/pubmed/31303791
http://dx.doi.org/10.2147/CMAR.S200907