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1D and 2D-HSQC NMR: Two Methods to Distinguish and Characterize Heparin From Different Animal and Tissue Sources

The US Food and Drug Administration has encouraged the reintroduction of bovine heparin drug product to the US market to mitigate the risks of heparin shortages and potential adulteration or contamination of the primary source which is porcine heparin. Here, a 1D-NMR method was applied to compare he...

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Detalles Bibliográficos
Autores principales: Mauri, Lucio, Marinozzi, Maria, Phatak, Nisarga, Karfunkle, Michael, St. Ange, Kalib, Guerrini, Marco, Keire, David A., Linhardt, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610300/
https://www.ncbi.nlm.nih.gov/pubmed/31316989
http://dx.doi.org/10.3389/fmed.2019.00142