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1D and 2D-HSQC NMR: Two Methods to Distinguish and Characterize Heparin From Different Animal and Tissue Sources
The US Food and Drug Administration has encouraged the reintroduction of bovine heparin drug product to the US market to mitigate the risks of heparin shortages and potential adulteration or contamination of the primary source which is porcine heparin. Here, a 1D-NMR method was applied to compare he...
Autores principales: | Mauri, Lucio, Marinozzi, Maria, Phatak, Nisarga, Karfunkle, Michael, St. Ange, Kalib, Guerrini, Marco, Keire, David A., Linhardt, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610300/ https://www.ncbi.nlm.nih.gov/pubmed/31316989 http://dx.doi.org/10.3389/fmed.2019.00142 |
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