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Process Intensification for an Insect Antimicrobial Peptide Elastin-Like Polypeptide Fusion Produced in Redox-Engineered Escherichia coli

Peptides and proteins containing disulfide bonds can be produced in Escherichia coli by targeting the oxidizing periplasm, co-expressing isomerases or chaperons, refolding from inclusion bodies, or by using redox-engineered E. coli strains. Thus far, protein expression in glutathione reductase and t...

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Detalles Bibliográficos
Autores principales: Joachim, Mathias, Maguire, Nicolas, Schäfer, Johannes, Gerlach, Doreen, Czermak, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610315/
https://www.ncbi.nlm.nih.gov/pubmed/31316976
http://dx.doi.org/10.3389/fbioe.2019.00150