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Cell Line Derived Xenograft Mouse Models Are a Suitable in vivo Model for Studying Tumor Budding in Colorectal Cancer

Tumor budding (TB) is an important prognostic parameter in colorectal cancer (CRC) and associated with metastasis. However, the mechanisms of TB have not been fully elucidated and a major limitation is the absence of in vivo models. Here, we determine the suitability of human cell line derived xenog...

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Detalles Bibliográficos
Autores principales: Georges, Laurent M. C., De Wever, Olivier, Galván, José A., Dawson, Heather, Lugli, Alessandro, Demetter, Pieter, Zlobec, Inti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610335/
https://www.ncbi.nlm.nih.gov/pubmed/31316988
http://dx.doi.org/10.3389/fmed.2019.00139