Addressing the Missing Heritability Problem With the Help of Regulatory Features

Genome-wide association studies (GWASs) have successfully identified thousands of susceptibility loci for human complex diseases. However, missing heritability is still a challenging problem. Considering most GWAS loci are located in regulatory elements, we recently developed a pipeline named functi...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Shan-Shan, Guo, Yan, Yang, Tie-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610400/
https://www.ncbi.nlm.nih.gov/pubmed/31320792
http://dx.doi.org/10.1177/1176934319860861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610400/
https://www.ncbi.nlm.nih.gov/pubmed/31320792
http://dx.doi.org/10.1177/1176934319860861

Ejemplares similares