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Addressing the Missing Heritability Problem With the Help of Regulatory Features
Genome-wide association studies (GWASs) have successfully identified thousands of susceptibility loci for human complex diseases. However, missing heritability is still a challenging problem. Considering most GWAS loci are located in regulatory elements, we recently developed a pipeline named functi...
Autores principales: | Dong, Shan-Shan, Guo, Yan, Yang, Tie-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610400/ https://www.ncbi.nlm.nih.gov/pubmed/31320792 http://dx.doi.org/10.1177/1176934319860861 |
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