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Advances in the Physicochemical Profiling of Opioid Compounds of Therapeutic Interest

This review focuses on recent developments in the physicochemical profiling of morphine and other opioids. The acid‐base properties and lipophilicity of these compounds is discussed at the microscopic, species‐specific level. Examples are provided where this type of information can reveal the mechan...

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Detalles Bibliográficos
Autores principales: Mazák, Károly, Noszál, Béla, Hosztafi, Sándor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610444/
https://www.ncbi.nlm.nih.gov/pubmed/31312587
http://dx.doi.org/10.1002/open.201900115