Cargando…

Using genetically incorporated unnatural amino acids to control protein functions in mammalian cells

Genetic code expansion allows unnatural (non-canonical) amino acid incorporation into proteins of interest by repurposing the cellular translation machinery. The development of this technique has enabled site-specific incorporation of many structurally and chemically diverse amino acids, facilitatin...

Descripción completa

Detalles Bibliográficos
Autores principales: Nödling, Alexander R., Spear, Luke A., Williams, Thomas L., Luk, Louis Y.P., Tsai, Yu-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610526/
https://www.ncbi.nlm.nih.gov/pubmed/31092687
http://dx.doi.org/10.1042/EBC20180042