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Using genetically incorporated unnatural amino acids to control protein functions in mammalian cells
Genetic code expansion allows unnatural (non-canonical) amino acid incorporation into proteins of interest by repurposing the cellular translation machinery. The development of this technique has enabled site-specific incorporation of many structurally and chemically diverse amino acids, facilitatin...
Autores principales: | Nödling, Alexander R., Spear, Luke A., Williams, Thomas L., Luk, Louis Y.P., Tsai, Yu-Hsuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610526/ https://www.ncbi.nlm.nih.gov/pubmed/31092687 http://dx.doi.org/10.1042/EBC20180042 |
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