Cargando…
PERK-Mediated Unfolded Protein Response Activation and Oxidative Stress in PARK20 Fibroblasts
PARK20, an early onset autosomal recessive parkinsonism is due to mutations in the phosphatidylinositol-phosphatase Synaptojanin 1 (Synj1). We have recently shown that the early endosomal compartments are profoundly altered in PARK20 fibroblasts as well as the endosomal trafficking. Here, we report...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610533/ https://www.ncbi.nlm.nih.gov/pubmed/31316342 http://dx.doi.org/10.3389/fnins.2019.00673 |