An optimised tissue disaggregation and data processing pipeline for characterising fibroblast phenotypes using single-cell RNA sequencing

Single-cell RNA sequencing (scRNA-Seq) provides a valuable platform for characterising multicellular ecosystems. Fibroblasts are a heterogeneous cell type involved in many physiological and pathological processes, but remain poorly-characterised. Analysis of fibroblasts is challenging: these cells a...

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Detalles Bibliográficos
Autores principales: Waise, Sara, Parker, Rachel, Rose-Zerilli, Matthew J. J., Layfield, David M., Wood, Oliver, West, Jonathan, Ottensmeier, Christian H., Thomas, Gareth J., Hanley, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610623/
https://www.ncbi.nlm.nih.gov/pubmed/31270426
http://dx.doi.org/10.1038/s41598-019-45842-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610623/
https://www.ncbi.nlm.nih.gov/pubmed/31270426
http://dx.doi.org/10.1038/s41598-019-45842-4

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