PRC1 collaborates with SMCHD1 to fold the X-chromosome and spread Xist RNA between chromosome compartments

X-chromosome inactivation triggers fusion of A/B compartments to inactive X (Xi)-specific structures known as S1 and S2 compartments. SMCHD1 then merges S1/S2s to form the Xi super-structure. Here, we ask how S1/S2 compartments form and reveal that Xist RNA drives their formation via recruitment of...

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Detalles Bibliográficos
Autores principales: Wang, Chen-Yu, Colognori, David, Sunwoo, Hongjae, Wang, Danni, Lee, Jeannie T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610634/
https://www.ncbi.nlm.nih.gov/pubmed/31270318
http://dx.doi.org/10.1038/s41467-019-10755-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610634/
https://www.ncbi.nlm.nih.gov/pubmed/31270318
http://dx.doi.org/10.1038/s41467-019-10755-3

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