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Pro-inflammatory role of NLRP3 inflammasome in experimental sterile corneal inflammation

We evaluated the role of NLR family pyrin domain containing 3 (NLRP3) inflammasome in sterile corneal inflammation caused by lipopolysaccharide (LPS) or alkali burns in C57BL6 mice or NLRP3 KO (Nlrp3(−/−)) mice. Various molecules related to the NLRP3 inflammasome were upregulated in C57BL6 mice afte...

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Detalles Bibliográficos
Autores principales: Shimizu, Hiroaki, Sakimoto, Tohru, Yamagami, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610657/
https://www.ncbi.nlm.nih.gov/pubmed/31270454
http://dx.doi.org/10.1038/s41598-019-46116-9