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Targeting Exosomal EBV-LMP1 Transfer and miR-203 Expression via the NF-κB Pathway: The Therapeutic Role of Aspirin in NPC

Nasopharyngeal carcinoma (NPC) is an invasive head-and-neck tumor with Epstein-Barr virus (EBV) as an important etiological cause. The EBV oncoprotein Latent membrane protein 1 (LMP1) can be trafficked into exosomes with unclear roles, and this trafficking is a potential problem in NPC control. Micr...

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Detalles Bibliográficos
Autores principales: Zuo, Lielian, Xie, Yan, Tang, Jinyong, Xin, Shuyu, Liu, Lingzhi, Zhang, Siwei, Yan, Qijia, Zhu, Fanxiu, Lu, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610683/
https://www.ncbi.nlm.nih.gov/pubmed/31265948
http://dx.doi.org/10.1016/j.omtn.2019.05.023