Rapamycin Rescues Age-Related Changes in Muscle-Derived Stem/Progenitor Cells from Progeroid Mice

Aging-related loss of adult stem cell function contributes to impaired tissue regeneration. Mice deficient in zinc metalloproteinase STE24 (Zmpste24(−/−)) exhibit premature age-related musculoskeletal pathologies similar to those observed in children with Hutchinson-Gilford progeria syndrome (HGPS)....

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Detalles Bibliográficos
Autores principales: Kawakami, Yohei, Hambright, William S., Takayama, Koji, Mu, Xiaodong, Lu, Aiping, Cummins, James H., Matsumoto, Tomoyuki, Yurube, Takashi, Kuroda, Ryosuke, Kurosaka, Masahiro, Fu, Freddie H., Robbins, Paul D., Niedernhofer, Laura J., Huard, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610712/
https://www.ncbi.nlm.nih.gov/pubmed/31312666
http://dx.doi.org/10.1016/j.omtm.2019.05.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610712/
https://www.ncbi.nlm.nih.gov/pubmed/31312666
http://dx.doi.org/10.1016/j.omtm.2019.05.011

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