Vitamin D/Vitamin D Receptor Signaling Is Required for Normal Development and Function of Group 3 Innate Lymphoid Cells in the Gut

Group 3 innate lymphoid cells (ILC3) play key roles in protective immunity and mucosal barrier maintenance. Here we showed that vitamin D/vitamin D receptor (VDR) signaling regulates gut ILC3. VDR deletion or 1,25-dihydroxyvitamin D deficiency in mice led to a marked reduction in colonic ILC3 popula...

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Detalles Bibliográficos
Autores principales: He, Lei, Zhou, Min, Li, Yan Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610723/
https://www.ncbi.nlm.nih.gov/pubmed/31272068
http://dx.doi.org/10.1016/j.isci.2019.06.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610723/
https://www.ncbi.nlm.nih.gov/pubmed/31272068
http://dx.doi.org/10.1016/j.isci.2019.06.026

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