Alterations in Organismal Physiology, Impaired Stress Resistance, and Accelerated Aging in Drosophila Flies Adapted to Multigenerational Proteome Instability

Being an assembly of highly sophisticated protein machines, cells depend heavily on proteostatic modules functionality and on adequate supply of energetic molecules for maintaining proteome stability. Yet, our understanding of the adaptations induced by multigenerational proteotoxic stress is limite...

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Detalles Bibliográficos
Autores principales: Manola, Maria S., Tsakiri, Eleni N., Trougakos, Ioannis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610734/
https://www.ncbi.nlm.nih.gov/pubmed/31320986
http://dx.doi.org/10.1155/2019/7823285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610734/
https://www.ncbi.nlm.nih.gov/pubmed/31320986
http://dx.doi.org/10.1155/2019/7823285

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