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Allelic variants of breast cancer susceptibility genes PALB2 and RECQL in the Latvian population

BACKGROUND: Large-scale case control studies revealed a number of moderate risk - low frequency breast cancer alleles of the PALB2 and RECQL genes. Some of these were reported as founder variants of Central and Eastern Europe. Based on highly similar founder variant spectra of the BRCA1 in Poland an...

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Detalles Bibliográficos
Autores principales: Hilz, Philip, Heinrihsone, Reicela, Pätzold, Lukas Alexander, Qi, Qi, Trofimovics, Genadijs, Gailite, Linda, Irmejs, Arvids, Gardovskis, Janis, Miklasevics, Edvins, Daneberga, Zanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610821/
https://www.ncbi.nlm.nih.gov/pubmed/31312277
http://dx.doi.org/10.1186/s13053-019-0116-6