Cathepsin L-induced galectin-1 may act as a proangiogenic factor in the metastasis of high-grade serous carcinoma

BACKGROUND: New treatment options for metastasised high-grade serous carcinoma (HGSC) are urgently needed. HGSC frequently metastasises to the omentum, inducing angiogenesis in the local omental microvasculature to facilitate tumour growth. We previously showed that HGSC-secreted cathepsin L (CathL)...

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Detalles Bibliográficos
Autores principales: Pranjol, Md Zahidul I., Zinovkin, Dmitry A., Maskell, Annelie R. T., Stephens, Laura J., Achinovich, Sergey L., Los’, Dmitry M., Nadyrov, Eldar A., Hannemann, Michael, Gutowski, Nicholas J., Whatmore, Jacqueline L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610868/
https://www.ncbi.nlm.nih.gov/pubmed/31269957
http://dx.doi.org/10.1186/s12967-019-1963-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610868/
https://www.ncbi.nlm.nih.gov/pubmed/31269957
http://dx.doi.org/10.1186/s12967-019-1963-7

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