The PPARγ agonist pioglitazone prevents TGF-β induced renal fibrosis by repressing EGR-1 and STAT3

BACKGROUND: It has been proposed that peroxisome proliferator-activated receptor-γ (PPARγ) agonists might reduce renal fibrosis, however, several studies had contradictory results. Moreover, the possible interaction of TGF-β(1), PPARγ, and transcription factors in renal fibrosis have not been invest...

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Detalles Bibliográficos
Autores principales: Németh, Ágnes, Mózes, Miklós M., Calvier, Laurent, Hansmann, Georg, Kökény, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610924/
https://www.ncbi.nlm.nih.gov/pubmed/31277592
http://dx.doi.org/10.1186/s12882-019-1431-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610924/
https://www.ncbi.nlm.nih.gov/pubmed/31277592
http://dx.doi.org/10.1186/s12882-019-1431-x

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