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Fueling the fire: emerging role of the hexosamine biosynthetic pathway in cancer
Altered metabolism and deregulated cellular energetics are now considered a hallmark of all cancers. Glucose, glutamine, fatty acids, and amino acids are the primary drivers of tumor growth and act as substrates for the hexosamine biosynthetic pathway (HBP). The HBP culminates in the production of a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610925/ https://www.ncbi.nlm.nih.gov/pubmed/31272438 http://dx.doi.org/10.1186/s12915-019-0671-3 |