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Fueling the fire: emerging role of the hexosamine biosynthetic pathway in cancer

Altered metabolism and deregulated cellular energetics are now considered a hallmark of all cancers. Glucose, glutamine, fatty acids, and amino acids are the primary drivers of tumor growth and act as substrates for the hexosamine biosynthetic pathway (HBP). The HBP culminates in the production of a...

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Detalles Bibliográficos
Autores principales:	Akella, Neha M., Ciraku, Lorela, Reginato, Mauricio J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610925/ https://www.ncbi.nlm.nih.gov/pubmed/31272438 http://dx.doi.org/10.1186/s12915-019-0671-3

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