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C3aR signaling and gliosis in response to neurodevelopmental damage in the cerebellum
BACKGROUND: Conditional ablation of the Smarca5 gene in mice severely impairs the postnatal growth of the cerebellum and causes an ataxic phenotype. Comparative gene expression studies indicated that complement-related proteins were upregulated in the cerebellum of Smarca5 mutant mice. Complement pr...
Autores principales: | Young, Kevin G., Yan, Keqin, Picketts, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610970/ https://www.ncbi.nlm.nih.gov/pubmed/31272467 http://dx.doi.org/10.1186/s12974-019-1530-4 |
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