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TLR4 participates in the transmission of ethanol-induced neuroinflammation via astrocyte-derived extracellular vesicles

BACKGROUND: Current evidence indicates that extracellular vesicles (EVs) participate in intercellular signaling, and in the regulation and amplification of neuroinflammation. We have previously shown that ethanol activates glial cells through Toll-like receptor 4 (TLR4) by triggering neuroinflammati...

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Detalles Bibliográficos
Autores principales: Ibáñez, Francesc, Montesinos, Jorge, Ureña-Peralta, Juan R., Guerri, Consuelo, Pascual, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610989/
https://www.ncbi.nlm.nih.gov/pubmed/31272469
http://dx.doi.org/10.1186/s12974-019-1529-x