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A novel mass spectrometry-cleavable, phosphate-based enrichable and multi-targeting protein cross-linker

Chemical cross-linking mass spectrometry (XL-MS) is a powerful technology for obtaining protein structural information and studying protein–protein interactions. We report phospho-bisvinylsulfone (pBVS) as a novel water-soluble, MS-cleavable, phosphate-based enrichable and multi-targeting cross-link...

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Detalles Bibliográficos
Autores principales: Huang, Rong, Zhu, Wei, Wu, Yue, Chen, Jiakang, Yu, Jianghui, Jiang, Biao, Chen, Hongli, Chen, Wenzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611067/
https://www.ncbi.nlm.nih.gov/pubmed/31341596
http://dx.doi.org/10.1039/c9sc00893d