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Molecular and in-silico analysis of single nucleotide polymorphism targeting human TP53 gene exon 5-8 in Sudanese esophageal cancer patients

Background: The protein product of the normal TP53 gene performs an essential function in cell cycle control and tumor suppression, and the mutation of a TP53 gene is an essential step in the development of many cancers. Despite the reported association of TP53 gene mutations with many human cancers...

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Detalles Bibliográficos
Autores principales: Elfaki, Rihab M., Abdelaziz, Mohammed S., Altayb, Hisham N., Munsoor, Munsoor M., Gameel, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611135/
https://www.ncbi.nlm.nih.gov/pubmed/31316750
http://dx.doi.org/10.12688/f1000research.15534.1