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Improvement in Tuberculosis Outcomes With a Combined Medical and Social Approach

Setting: Studies performed locally in Switzerland in the late eighties reported unsatisfactory treatment outcomes. Better outcomes were observed since the introduction of directly observed therapy (DOT) in the late nineties and improvement in social support in recent years. Design: retrospective stu...

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Autores principales: Mazza-Stalder, Jesica, Chevallier, Emilie, Opota, Onya, Carreira, Ana, Jaton, Katia, Masserey, Eric, Zellweger, Jean Pierre, Nicod, Laurent Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611410/
https://www.ncbi.nlm.nih.gov/pubmed/31316986
http://dx.doi.org/10.3389/fmed.2019.00135
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author Mazza-Stalder, Jesica
Chevallier, Emilie
Opota, Onya
Carreira, Ana
Jaton, Katia
Masserey, Eric
Zellweger, Jean Pierre
Nicod, Laurent Pierre
author_facet Mazza-Stalder, Jesica
Chevallier, Emilie
Opota, Onya
Carreira, Ana
Jaton, Katia
Masserey, Eric
Zellweger, Jean Pierre
Nicod, Laurent Pierre
author_sort Mazza-Stalder, Jesica
collection PubMed
description Setting: Studies performed locally in Switzerland in the late eighties reported unsatisfactory treatment outcomes. Better outcomes were observed since the introduction of directly observed therapy (DOT) in the late nineties and improvement in social support in recent years. Design: retrospective study of treatment outcomes for all tuberculosis (TB) patients notified in Vaud County (VD), Switzerland, between, 1st of January 2010 and 31st of December of 2014. Results: 375 patients were notified in VD during the study period. The global outcome was successful in 90.1% of patients (338/375). In 183 culture and PCR positive pulmonary TB, the documented cure rate was 57.9% (106/183), and the treatment completion was 59/183 (32.2%), i.e., a treatment success of 90.2%. DOT was applied globally in 234/375 (62.4%) and in 64/67 of the asylum seekers (AS) (95.5%) followed at the dispensary. Treatment outcomes were successful in 60/67 (89.6%) AS. Discussion: Improvements in tuberculosis outcomes resulted not only from the introduction of DOT in VD in the nineties but also from a change in the management, with increased attention to the social problems faced by the migrants. Conclusion: A combined medical and social approach of TB care in VD improved treatment outcomes.
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spelling pubmed-66114102019-07-17 Improvement in Tuberculosis Outcomes With a Combined Medical and Social Approach Mazza-Stalder, Jesica Chevallier, Emilie Opota, Onya Carreira, Ana Jaton, Katia Masserey, Eric Zellweger, Jean Pierre Nicod, Laurent Pierre Front Med (Lausanne) Medicine Setting: Studies performed locally in Switzerland in the late eighties reported unsatisfactory treatment outcomes. Better outcomes were observed since the introduction of directly observed therapy (DOT) in the late nineties and improvement in social support in recent years. Design: retrospective study of treatment outcomes for all tuberculosis (TB) patients notified in Vaud County (VD), Switzerland, between, 1st of January 2010 and 31st of December of 2014. Results: 375 patients were notified in VD during the study period. The global outcome was successful in 90.1% of patients (338/375). In 183 culture and PCR positive pulmonary TB, the documented cure rate was 57.9% (106/183), and the treatment completion was 59/183 (32.2%), i.e., a treatment success of 90.2%. DOT was applied globally in 234/375 (62.4%) and in 64/67 of the asylum seekers (AS) (95.5%) followed at the dispensary. Treatment outcomes were successful in 60/67 (89.6%) AS. Discussion: Improvements in tuberculosis outcomes resulted not only from the introduction of DOT in VD in the nineties but also from a change in the management, with increased attention to the social problems faced by the migrants. Conclusion: A combined medical and social approach of TB care in VD improved treatment outcomes. Frontiers Media S.A. 2019-06-21 /pmc/articles/PMC6611410/ /pubmed/31316986 http://dx.doi.org/10.3389/fmed.2019.00135 Text en Copyright © 2019 Mazza-Stalder, Chevallier, Opota, Carreira, Jaton, Masserey, Zellweger and Nicod. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Mazza-Stalder, Jesica
Chevallier, Emilie
Opota, Onya
Carreira, Ana
Jaton, Katia
Masserey, Eric
Zellweger, Jean Pierre
Nicod, Laurent Pierre
Improvement in Tuberculosis Outcomes With a Combined Medical and Social Approach
title Improvement in Tuberculosis Outcomes With a Combined Medical and Social Approach
title_full Improvement in Tuberculosis Outcomes With a Combined Medical and Social Approach
title_fullStr Improvement in Tuberculosis Outcomes With a Combined Medical and Social Approach
title_full_unstemmed Improvement in Tuberculosis Outcomes With a Combined Medical and Social Approach
title_short Improvement in Tuberculosis Outcomes With a Combined Medical and Social Approach
title_sort improvement in tuberculosis outcomes with a combined medical and social approach
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611410/
https://www.ncbi.nlm.nih.gov/pubmed/31316986
http://dx.doi.org/10.3389/fmed.2019.00135
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