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PARP-1 inhibitor modulate β-catenin signaling to enhance cisplatin sensitivity in cancer cervix
Cisplatin is a keystone for treatment of both recurring and locally advanced cervical cancer. However toxic side effects and acquired resistance limits its efficacy. Enhanced DNA repair is one of the mechanisms through which cancer cells acquire cisplatin resistance. Inhibitors of PARP, which is a D...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611509/ https://www.ncbi.nlm.nih.gov/pubmed/31303961 http://dx.doi.org/10.18632/oncotarget.27008 |