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AGR2, a unique tumor-associated antigen, is a promising candidate for antibody targeting

Anterior gradient 2 (AGR2), a protein disulfide isomerase, shows two subcellular localizations: intracellular (iAGR2) and extracellular (eAGR2). In healthy cells that express AGR2, the predominant form is iAGR2, which resides in the endoplasmic reticulum. In contrast, cancer cells secrete and expres...

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Detalles Bibliográficos
Autores principales: Liu, Alvin Y., Kanan, Adelle D., Radon, Tomasz P., Shah, Siama, Weeks, Mark E., Foster, Julie M., Sosabowski, Jane K., Dumartin, Laurent, Crnogorac-Jurcevic, Tatjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611513/
https://www.ncbi.nlm.nih.gov/pubmed/31303962
http://dx.doi.org/10.18632/oncotarget.26945