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Comparative RNA-seq analysis reveals dys-regulation of major canonical pathways in ERG-inducible LNCaP cell progression model of prostate cancer

Prostate Cancer (CaP) is the second leading cause of cancer related death in USA. In human CaP, gene fusion between androgen responsive regulatory elements at the 5'-untranslated region of TMPRSS2 and ETS-related genes (ERG) is present in at least 50% of prostate tumors. Here we have investigat...

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Detalles Bibliográficos
Autores principales: Kumar, Parameet, Chakraborty, Joyeeta, Sukumar, Gauthaman, Dalgard, Clifton, Chatterjee, Raghunath, Biswas, Roopa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611515/
https://www.ncbi.nlm.nih.gov/pubmed/31303963
http://dx.doi.org/10.18632/oncotarget.27019