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Doberman pinschers present autoimmunity associated with functional autoantibodies: A model to study the autoimmune background of human dilated cardiomyopathy

BACKGROUND: Autoimmunity associated with autoantibodies against the β1-adrenergic receptor (β1-AAB) is increasingly accepted as the driver of human dilated cardiomyopathy (DCM). Unfortunately, there is a lack of animal models to extend the knowledge about β1-AAB autoimmunity in DCM and to develop ap...

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Detalles Bibliográficos
Autores principales: Wess, Gerhard, Wallukat, Gerd, Fritscher, Anna, Becker, Niels-Peter, Wenzel, Katrin, Müller, Johannes, Schimke, Ingolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611557/
https://www.ncbi.nlm.nih.gov/pubmed/31276517
http://dx.doi.org/10.1371/journal.pone.0214263