Unusual, stable replicating viruses generated from mumps virus cDNA clones

In reverse genetic experiments we have isolated recombinant mumps viruses (rMuV) that carry large numbers of mutations clustered in small parts of their genome, which are not caused by biased hyper-mutation. In two separate experiments we obtained such recombinant viruses: one virus had 11 mutations...

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Detalles Bibliográficos
Autores principales: Bamford, Connor, Wignall-Fleming, Elizabeth, Sreenu, Vattipally B., Randall, Richard, Duprex, Paul, Rima, Bertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611571/
https://www.ncbi.nlm.nih.gov/pubmed/31276568
http://dx.doi.org/10.1371/journal.pone.0219168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611571/
https://www.ncbi.nlm.nih.gov/pubmed/31276568
http://dx.doi.org/10.1371/journal.pone.0219168

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