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Unusual, stable replicating viruses generated from mumps virus cDNA clones
In reverse genetic experiments we have isolated recombinant mumps viruses (rMuV) that carry large numbers of mutations clustered in small parts of their genome, which are not caused by biased hyper-mutation. In two separate experiments we obtained such recombinant viruses: one virus had 11 mutations...
Autores principales: | Bamford, Connor, Wignall-Fleming, Elizabeth, Sreenu, Vattipally B., Randall, Richard, Duprex, Paul, Rima, Bertus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611571/ https://www.ncbi.nlm.nih.gov/pubmed/31276568 http://dx.doi.org/10.1371/journal.pone.0219168 |
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