Combination of fenretinide and ABT-263 induces apoptosis through NOXA for head and neck squamous cell carcinoma treatment

The overall survival for recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) remains low, with little progress made over decades. Cisplatin, most frequently used for HNSCC treatment, activates mitochondria-dependent apoptosis through the BCL-2 family proteins. We have previously de...

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Detalles Bibliográficos
Autores principales: Britt, Erin L., Raman, Sarina, Leek, Kendall, Sheehy, Casey H., Kim, Sung W., Harada, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611623/
https://www.ncbi.nlm.nih.gov/pubmed/31276572
http://dx.doi.org/10.1371/journal.pone.0219398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611623/
https://www.ncbi.nlm.nih.gov/pubmed/31276572
http://dx.doi.org/10.1371/journal.pone.0219398

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