Cargando…

RHO-1 and the Rho GEF RHGF-1 interact with UNC-6/Netrin signaling to regulate growth cone protrusion and microtubule organization in Caenorhabditis elegans

UNC-6/Netrin is a conserved axon guidance cue that directs growth cone migrations in the dorsal-ventral axis of C. elegans and in the vertebrate spinal cord. UNC-6/Netrin is expressed in ventral cells, and growth cones migrate ventrally toward or dorsally away from UNC-6/Netrin. Recent studies of gr...

Descripción completa

Detalles Bibliográficos
Autores principales: Gujar, Mahekta R., Stricker, Aubrie M., Lundquist, Erik A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611649/
https://www.ncbi.nlm.nih.gov/pubmed/31233487
http://dx.doi.org/10.1371/journal.pgen.1007960