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Competition for hosts modulates vast antigenic diversity to generate persistent strain structure in Plasmodium falciparum
In their competition for hosts, parasites with antigens that are novel to the host immune system will be at a competitive advantage. The resulting frequency-dependent selection can structure parasite populations into strains of limited genetic overlap. For the causative agent of malaria, Plasmodium...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611651/ https://www.ncbi.nlm.nih.gov/pubmed/31233490 http://dx.doi.org/10.1371/journal.pbio.3000336 |