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Competition for hosts modulates vast antigenic diversity to generate persistent strain structure in Plasmodium falciparum

In their competition for hosts, parasites with antigens that are novel to the host immune system will be at a competitive advantage. The resulting frequency-dependent selection can structure parasite populations into strains of limited genetic overlap. For the causative agent of malaria, Plasmodium...

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Detalles Bibliográficos
Autores principales: Pilosof, Shai, He, Qixin, Tiedje, Kathryn E., Ruybal-Pesántez, Shazia, Day, Karen P., Pascual, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611651/
https://www.ncbi.nlm.nih.gov/pubmed/31233490
http://dx.doi.org/10.1371/journal.pbio.3000336